Site Name: Belgium-Rixensart
Posted Date: Nov 6 2024
Job Purpose
The Principal Scientist is expected to lead, design and execute preclinical scientific studies in support of vaccine projects or technological platforms in discovery, development, or life cycle management. They may have a team to manage.
Key Responsibilities
* Lead the design, planning, organization, and analysis of preclinical studies (internal and external), including resource forecasts and activity planning.
* Direct management or support to N+1 in development and supervision of lab technicians, requiring adequate presence on the shop floor where associated activities are performed. May participate in the performance evaluation and development plan of laboratory staff.
* Share expertise in multiple technical competency domains across the preclinical department BE and possibly across Scientific Areas; conduct scientific/technology watch in own competency domain within defined mission or project.
* Lead the development and implementation of new technologies and ensure alignment and state of the art for a given technology across the preclinical department, applying and referring to GxP/EHS/QA rules in their team/lab.
* Lead the development of new Read Outs/Laboratory Assays (when applicable).
* Active participation and presentation of lab results in internal meetings, working groups, and technical and project team meetings, ensuring quality interpretation and extensive quality checks of raw data.
* Act as the preclinical representative to project teams; when specific expert in one or more techniques, serve as the principal representative at technical development teams and preferred point of contact for TRD QC and VCLAP departments regarding analytical testing or read-outs. Autonomous in decision-making within their area of scientific or technical competencies with direct impact on related project strategy.
* Autonomous in writing experimental procedures and scientific reports. Significant contribution (autonomous writing and review by N+1) to and direct interactions with the Regulatory/IP teams for the preparation of the preclinical section of Regulatory/IP documents, in their area of technical expertise.
* Responsible for the immunogenicity testing phase (non-GLP conditions) which is part of GLP Toxicity studies, according to the L-SOP9*5529, when applicable.
* Lead the development/qualification of release/characterization assays and testing of Phase I/II vaccine lots before transfer to ARD, when applicable.
* May coordinate clinical exploratory testing according to best practices and GSK SOP/Policies, when applicable.
Why you?
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
* PhD with 3+ years of post-doc and/or job-related experience.
* Area of specialization: Virology (respiratory viruses and/or herpesviruses) and Immunology with a strong expertise in related laboratory assays.
* A good understanding of the biopharma/vaccine development process.
* Total education and experience in biopharma-related fields and in respiratory virus or herpesviruses of at least 8 years.
* Strong expertise in Immunology and Virology mandatory.
Preferred Qualifications:
If you have the following characteristics, it would be a plus:
* Ability to work with cross-functional teams and communicate effectively.
* Fluent English is a must.
* Sound scientific methodology and thinking.
* Excellent presentation and communication skills.
* Innovative thinking and solution-oriented.
If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require to make suitable arrangements.
Why GSK?
GSK is a global biopharma company with a special purpose – to unite science, technology, and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/immunology, and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged, and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
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