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Associate Scientist in Sizing & Morphology Platform, Analytical R&D, Rixensart
Client:
1849 GlaxoSmithKline Biologicals S.A.
Location:
Rixensart
Job Category:
Other
EU work permit required:
Yes
Job Reference:
bc9f976f5361
Job Views:
25
Posted:
23.01.2025
Expiry Date:
09.03.2025
Job Description:
As an Associate Scientist of the Sizing & Morphology platform in Analytical R&D (ARD), you will plan & execute lab activities in a team in charge of size based separations & light scattering techniques. Also, you will participate in the analytical method development according to Quality by Design principles, from early vaccine candidates up to validation for phase III programs.
Your responsibilities:
* You will plan & execute lab activities (Analytical Ultracentrifugation AUC, Dynamic Light Scattering DLS, and Size Exclusion Chromatography SEC) in the GMP (Wavre) and non GMP (Rixensart) environment.
* You will provide support and technical advice to lab technicians and participate in the planning of their activities.
* You will participate in lab organization and maintenance, e.g., ordering reagents and follow up of instruments maintenance/repair in collaboration with technicians & lab supports.
* You will participate in method development according to Quality by Design (QbD) guidelines, in a phase appropriate manner, and provide fit for purpose analytical methods in interaction with Analytical Product Leaders & Subteams (APL & AST), as well as Industrialization Leaders (AIL).
* You will interpret and report results after an extensive check of the raw data quality and participate in the double check of results.
* You will be involved in generating appropriate analytical documentation, including procedures, protocols, and reports (development, technical, qualification, validation).
* You will present results in internal meetings (within the team, to ASTs, etc.).
* You will interact with other Technical R&D (TRD) departments (Drug Substance, Drug Product, Statisticians team), as well as the Preclinical department or GIO/QC organizations.
* You will participate in scientific/technology watch in your domain of competency.
Basic Qualifications:
1. Master''s degree in Chemistry, Biochemistry, Biophysics, Biology, Bioengineering, Chemical Engineering, Pharmacy, or other relevant discipline.
2. Extensive experience in DLS and AUC.
3. Strong experience in working in a GMP environment.
4. Experience in size exclusion chromatography (HPSEC) is a plus.
5. Awareness of Quality by Design principles.
6. Knowledge of method qualification/validation principles.
7. Sound scientific methodology and thinking, autonomy, and commitment to solving problems and bringing i